It is also known as trisomy 21, is caused by the presence of an extra copy of chromosome 21. This condition results from numerical abnormalities in the chromosomes, specifically an additional copy of chromosome 21, leading to developmental and intellectual disabilities, characteristic facial features, and various health issues. It is the most common chromosomal disorder and is associated with an extra chromosome in the pair 21, rather than the sex chromosomes.
The civilization existed between- 2550 BC- 1500 BC Period of Mature Harappan Culture – 2550 BC- 1900 BC Period of Post urban phase of Harappa- 1900 BC- 1500 BC (1200 BC at some places ) The Indus civilisation is also called Harappan because “Dayaram Sahni” in the year 1921 first discovered Harappa, which is presently situated in West Punjab province of Pakistan. The civilisation was extended over an Area - 1299600 Square Kilometre which was bigger than contemporary Ancient Egypt & Mesopotamia Civilisation. Spread over area of the Civilisation was as follows; North- Manda in Jammu & Ropar in Punjab South- Daimabad in Maharashtra & Bhagatrav in Gujarat i.e. up to Narmada River estuary East- Bargaon, Manpur & Allamgirpur in West Meerut district of Uttar Pradesh. West- Sutkah-Koh ...
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